Sodium–glucose linked transporter-2 inhibitors: potential for renoprotection beyond blood glucose lowering?
نویسندگان
چکیده
منابع مشابه
Sodium-Glucose Linked Transporter-2 Inhibitors in Chronic Kidney Disease
SGLT2 inhibitors are new antihyperglycaemic agents whose ability to lower glucose is directly proportional to GFR. Therefore, in chronic kidney disease (CKD) the blood glucose lowering effect is reduced. Unlike many current therapies, the mechanism of action of SGLT2 inhibitors is independent of insulin action or beta-cell function. In addition, the mechanism of action of SGLT2 inhibitors is co...
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ژورنال
عنوان ژورنال: Kidney International
سال: 2014
ISSN: 0085-2538
DOI: 10.1038/ki.2013.451